MICA allele-level typing by sequence-based typing with computerized assignment of polymorphic sites and short tandem repeats within the transmembrane region.

@article{Zou2006MICAAT,
  title={MICA allele-level typing by sequence-based typing with computerized assignment of polymorphic sites and short tandem repeats within the transmembrane region.},
  author={Yizhou Zou and Mei Han and Zhengnan Wang and Peter Stastny},
  journal={Human immunology},
  year={2006},
  volume={67 3},
  pages={
          145-51
        }
}
MICA genes are located close to, but are structurally distinct from, HLA class I genes and have been found to be associated with some diseases and with immune responses to transplants. We have developed a MICA typing method based on polymerase chain reaction (PCR)/sequence-based typing and a computer program that determines the polymorphisms and distinguishes the GCT repeats in exon 5. One PCR amplification was performed to obtain templates of 2.2 kb including exons 2, 3, 4, and 5 of MICA to be… CONTINUE READING
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