MICA Expression Is Regulated by Cell Adhesion and Contact in a FAK/Src-Dependent Manner

Abstract

MICA is a major ligand for the NKG2D immune receptor, which plays a key role in activating natural killer (NK) cells and cytotoxic T cells. We analyzed NKG2D ligand expression on a range of cell types and could demonstrate that MICA expression levels were closely linked to cellular growth mode. While the expression of other NKG2D ligands was largely… (More)
DOI: 10.3389/fimmu.2016.00687

Topics

  • Presentations referencing similar topics