MIAX: a system for assessment of macromolecular interaction. 3) A parallel hybrid GA for flexible protein docking.

@article{Carpio2000MIAXAS,
  title={MIAX: a system for assessment of macromolecular interaction. 3) A parallel hybrid GA for flexible protein docking.},
  author={Carlos Adriel Del Carpio and Atsushi Yoshimori},
  journal={Genome informatics. Workshop on Genome Informatics},
  year={2000},
  volume={11},
  pages={205-14}
}
We propose a parallel hybrid genetic algorithm for flexible protein-protein docking in order to improve the conventional rigid-body models to manipulate protein-protein interactions. The proposed hybrid algorithm is a combination of an evolutionary algorithm with a simulated annealing one, yielding a powerful protein-complex conformation-searching engine. Parallelization of the procedure makes possible to reach high algorithm performance, in both, execution times and size of treated monomers… CONTINUE READING