MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis.

@article{VzquezGarca1998MHCCI,
  title={MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis.},
  author={M N V{\'a}zquez-Garc{\'i}a and Carmen Al{\'a}ez and Alessandro Olivo and H{\'e}ctor Debaz and Elva P{\'e}rez-Luque and Ana I Burguete and Stefan Cano and Gloria de la Rosa and Norman Bautista and Alicia Hern{\'a}ndez and Juan Pedro Bandera and L. F. Bloomfield Torres and David Kershenobich and Fernando Alvarez and Clara Gorodezky},
  journal={Journal of hepatology},
  year={1998},
  volume={28 6},
  pages={985-90}
}
BACKGROUND/AIMS Autoimmune hepatitis has a genetic background associated with different HLA DRB1 alleles depending on the ethnic group. The aim of this study was to analyse the immunogenetics of type I autoimmune hepatitis in Mexicans. METHODS Thirty Mexican Mestizo patients and 175 healthy controls were HLA typed as follows: class I antigens were determined by microlymphocytotoxicity and class II typing was done on DNA samples using PCR-SSO and PCR-SSP for DRB1, DQA1 and DQB1 loci. RESULTS… CONTINUE READING

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