MHC class II molecules, cathepsins, and La/SSB proteins in lacrimal acinar cell endomembranes.


Sjögren's syndrome is a chronic autoimmune disease affecting the lacrimal glands and other epithelia. It has been suggested that acinar cells of the lacrimal glands provoke local autoimmune responses, leading to Sjögren's syndrome when they begin expressing major histocompatibility complex (MHC) class II molecules. We used isopycnic centrifugation and phase… (More)
DOI: 10.1152/ajpcell.1999.277.5.C994

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