MHC-based fiber type and E-C coupling characteristics in mechanically skinned muscle fibers of the rat.

@article{Goodman2003MHCbasedFT,
  title={MHC-based fiber type and E-C coupling characteristics in mechanically skinned muscle fibers of the rat.},
  author={Craig A Goodman and Michael F. Patterson and Gabriela M. M. Stephenson},
  journal={American journal of physiology. Cell physiology},
  year={2003},
  volume={284 6},
  pages={C1448-59}
}
In this study, we investigated whether the previously established differences between fast- and slow-twitch single skeletal muscle fibers of the rat, in terms of myosin heavy chain (MHC) isoform composition and contractile function, are also detectable in excitation-contraction (E-C) coupling. We compared the contractile responsiveness of electrophoretically typed, mechanically skinned single fibers from the soleus (Sol), the extensor digitorum longus (EDL), and the white region of the… CONTINUE READING

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