MHC antigen expression and cellular response in spontaneous and induced rejection of intracerebral neural xenografts in neonatal rats.

@article{Pollack1990MHCAE,
  title={MHC antigen expression and cellular response in spontaneous and induced rejection of intracerebral neural xenografts in neonatal rats.},
  author={I. Pollack and R. Lund and K. Rao},
  journal={Restorative neurology and neuroscience},
  year={1990},
  volume={1 5},
  pages={
          347-60
        }
}
  • I. Pollack, R. Lund, K. Rao
  • Published 1990
  • Biology, Medicine
  • Restorative neurology and neuroscience
  • Fetal mouse retinae transplanted to the mesencephalon of neonatal rats generally survive for prolonged periods of time without immune suppression suggesting that such grafts enjoy a degree of immunological privilege. A small, but consistent percentage of these transplants, however, ultimately undergo spontaneous rejection. In addition, rejection can be induced by (1) systemically sensitizing the host to the donor antigens by placing a mouse skin graft or (2) producing a local degenerative… CONTINUE READING
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