MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin.

@article{Gollapudi2008MGN3BiobranMA,
  title={MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin.},
  author={Sastry V. R. S. Gollapudi and Mamdooh H Ghoneum},
  journal={Cancer detection and prevention},
  year={2008},
  volume={32 1},
  pages={1-6}
}
BACKGROUND MGN-3/Biobran, a modified form of arabinoxylan from rice bran, is a potent biological response modifier (BRM). Our previous studies demonstrated that MGN-3 sensitizes human leukemia cells to death receptor [CD95]-induced apoptosis [Ghoneum M, Gollapudi S. MGN-3 sensitizes human T cell leukemia cells to death receptor (CD95)-induced apoptosis. Cancer Lett 2003;201:41-9]. In this study, we evaluated the chemo-sensitizing activity of MGN-3 against human breast cancer cells (BCCs) in… CONTINUE READING

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Modified arabinoxylan rice bran (MGN-3/ Biobran) potentiates apoptosis in cancer cells induced by multiple anti-cancer agents in vitro

  • M Ghoneum, S. Gollapudi
  • Proceedings of the 7th international symposium on…
  • 2004
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