MG53 regulates membrane budding and exocytosis in muscle cells.

  title={MG53 regulates membrane budding and exocytosis in muscle cells.},
  author={Chuanxi Cai and Haruko Masumiya and Noah L Weisleder and Zui Pan and Miyuki Nishi and Shinji Komazaki and Hiroshi Takeshima and Jianjie Ma},
  journal={The Journal of biological chemistry},
  volume={284 5},
Membrane recycling and remodeling contribute to multiple cellular functions, including cell fusion events during myogenesis. We have identified a tripartite motif (TRIM72) family member protein named MG53 and defined its role in mediating the dynamic process of membrane fusion and exocytosis in striated muscle. MG53 is a muscle-specific protein that contains a TRIM motif at the amino terminus and a SPRY motif at the carboxyl terminus. Live cell imaging of green fluorescent protein-MG53 fusion… CONTINUE READING
40 Citations
1 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 40 extracted citations


Publications referenced by this paper.

hp://w w w D

  • P. L. McNeil, T. Kirchhausen
  • Nat Rev Mol Cell Biol 6,
  • 2005

Similar Papers

Loading similar papers…