MF59 adjuvanted seasonal and pandemic influenza vaccines.

  title={MF59 adjuvanted seasonal and pandemic influenza vaccines.},
  author={Theodore F. Tsai},
  journal={Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan},
  volume={131 12},
  • Theodore F. Tsai
  • Published 2011 in
    Yakugaku zasshi : Journal of the Pharmaceutical…
MF59-adjuvanted seasonal trivalent inactivated (ATIV) vaccine licensed since 1997 and MF59-adjuvanted pandemic H1N1 vaccines have been distributed to approximately 80M persons. Addition of the emulsion adjuvant to inactivated vaccine formulations provides for higher levels of antibody to the viral hemagglutinin (HA) in less responsive older adults, infants and children which, in the case of the pandemic vaccine, allowed only 3.75 µg of the HA to be immunogenic. The adjuvant also stimulates… CONTINUE READING
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