METHYLATION OF SEROTONIN RECEPTOR 3A IN ADHD, BORDERLINE PERSONALITY, AND BIPOLAR DISORDERS: LINK WITH SEVERITY OF THE DISORDERS AND CHILDHOOD MALTREATMENT

@article{Perroud2016METHYLATIONOS,
  title={METHYLATION OF SEROTONIN RECEPTOR 3A IN ADHD, BORDERLINE PERSONALITY, AND BIPOLAR DISORDERS: LINK WITH SEVERITY OF THE DISORDERS AND CHILDHOOD MALTREATMENT},
  author={N. Perroud and S. Zewdie and L. Stenz and W. Adouan and S. Bavamian and P. Prada and R. Nicastro and R. Hasler and A. Nallet and C. Piguet and A. Paoloni-Giacobino and J. Aubry and A. Dayer},
  journal={Depression and Anxiety},
  year={2016},
  volume={33}
}
Serotonin 3A receptor (5‐HT3AR) is associated at the genetic and epigenetic levels with a variety of psychiatric disorders and interacts with early‐life stress such as childhood maltreatment. We studied the impact of childhood maltreatment on the methylation status of the 5‐HT3AR and its association with clinical severity outcomes in relation with a functional genetic polymorphism. 
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[Childhood maltreatment and its impact on the mental health].
This review covers the literature of the last 25 years on the impact of childhood maltreatment on the mental health throughout the individual's life. Child abuse increases the risk of many mentalExpand
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