METHOD DEVELOPMENT AND VALIDATION FOR DISSOLUTION METHOD OF TOLVAPTAN IN BULK AND TABLET DOSAGE FORM BY UV SPECTROPHOTOMETRY

@inproceedings{Murugan2013METHODDA,
  title={METHOD DEVELOPMENT AND VALIDATION FOR DISSOLUTION METHOD OF TOLVAPTAN IN BULK AND TABLET DOSAGE FORM BY UV SPECTROPHOTOMETRY},
  author={Sengottaiyan Murugan and Nathireddy Pavankumar and Ch Kirankumar and Syam Sundhar and Sabbineni Harika and P. Satya Anusha},
  year={2013}
}
A simple, sensitive, accurate, precise and rapid UV spectrophotometric method was developed for the estimation of Tolvaptan in pure form and its formulation. For the estimation of Tolvaptan, solvent system employed was Methanol and Dissolution medium (0.01N Hydrochloric acid + 1% Sodium Lauryl Sulphate) and wavelength of detection was 269nm .The developed method was used to estimate the total drug content in commercially available oral formulation of Tolvaptan and recovery studies were carried… CONTINUE READING

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