MET Is Required for the Maximal Action of 20-Hydroxyecdysone during Bombyx Metamorphosis

@inproceedings{Guo2012METIR,
  title={MET Is Required for the Maximal Action of 20-Hydroxyecdysone during Bombyx Metamorphosis},
  author={Enen Guo and Qianyu He and ShuMin Liu and Ling Tian and Zhentao Sheng and Qin Peng and Jingmin Guan and Mingan Shi and Kang Li and Lawrence I. Gilbert and Jian Wang and Yuanpeng Cao and Sheng Li},
  booktitle={PloS one},
  year={2012}
}
Little is known about how the putative juvenile hormone (JH) receptor, the bHLH-PAS transcription factor MET, is involved in 20-hydroxyecdysone (20E; the molting hormone) action. Here we report that two MET proteins found in the silkworm, Bombyx mori, participate in 20E signal transduction. Met is 20E responsive and its expression peaks during molting and pupation, when the 20E titer is high. As found with results from RNAi knockdown of EcR-USP (the ecdysone receptor genes), RNAi knockdown of… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 51 references

Transcriptional regulation of juvenile hormone-mediated induction of Krüppel homolog 1, a repressor of insect metamorphosis.

Proceedings of the National Academy of Sciences of the United States of America • 2012
View 4 Excerpts
Highly Influenced

Heterodimer of two bHLH-PAS proteins mediates juvenile hormone-induced gene expression.

Proceedings of the National Academy of Sciences of the United States of America • 2011
View 10 Excerpts
Highly Influenced

Interaction of proteins involved in ecdysone and juvenile hormone signal transduction.

Archives of insect biochemistry and physiology • 2009
View 9 Excerpts
Highly Influenced

Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 9 Excerpts
Highly Influenced

The ecdysteroid receptor

VC Henrich
Insect Endocrinology, • 2012
View 1 Excerpt

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