MERCI 1: A Phase 1 Study of Mechanical Embolus Removal in Cerebral Ischemia

@article{Gobin2004MERCI1A,
  title={MERCI 1: A Phase 1 Study of Mechanical Embolus Removal in Cerebral Ischemia},
  author={Y. Pierre Gobin and Sidney Starkman and Gary R. Duckwiler and Thomas J. Grobelny and Chelsea S. Kidwell and R. Jahan and John Pile-Spellman and A Z Segal and Fernando Vi{\~n}uela and Jeffrey L. Saver},
  journal={Stroke},
  year={2004},
  volume={35},
  pages={2848-2853}
}
Background and Purpose— To report the result of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) 1 study, a phase 1 trial to evaluate the safety and efficacy of mechanical embolectomy in the cerebral vasculature. Methods— MERCI 1 enrolled 30 patients in 7 US centers. Main inclusion criteria were: National Institutes of Health Stroke Scale score (NIHSS) ≥10; treatment performed within 8 hours from symptoms onset and contra-indication to intravenous thrombolysis; no large hypodensity… Expand
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