MENTAL DISTRUBANCES FOLLOWED BY STUPOR IN A PATIENT WITH CARCINOIDOSIS: Recovery with Tryptophan treatment

@article{Lehmann1966MENTALDF,
  title={MENTAL DISTRUBANCES FOLLOWED BY STUPOR IN A PATIENT WITH CARCINOIDOSIS: Recovery with Tryptophan treatment},
  author={J{\o}rgen Erik Lehmann},
  journal={Acta Psychiatrica Scandinavica},
  year={1966},
  volume={42}
}
  • J. Lehmann
  • Published 1 June 1966
  • Medicine, Psychology
  • Acta Psychiatrica Scandinavica
This report deals with a case of carcinoidosis in which the patient displayed severe mental disturbances. With therapy consisting of a high dose of tryptophan administered intravenously and by stomach tube together with a serotonin inhibitor the patient recovered and assumed a fairly normal mental state within 24 hours. Temporary relapses, presumably due to a decreased supply of tryptophan, could be corrected by further doses of the substance, and normal mental behaviour could then be… 
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Tryptophan in the treatment of carcinoid crisis

Tryptophan may have a supportive role in the management of carcinoid crisis and its level of consciousness improved and blood tryptophan increased to 10 μg/ml after treatment with 3.4 g tryPTophan daily.

Catatonia: the Tension Insanity

  • John Johnson
  • Psychology, Medicine
    British Journal of Psychiatry
  • 1993
Catatonia is now best considered as a neuropsychiatric syndrome due to a wide variety of organic disease processes, manifest in catelepsy in a setting of an abnormal mental state, most commonly an affective disorder.

Tryptophan malabsorption in levodopa-treated parkinsonian patients. Effect of tryptophan on mental disturbances.

  • J. Lehmann
  • Medicine, Biology
    Acta medica Scandinavica
  • 1973
Mental disturbances were observed in cases with extremely low serum Try values and were presumed to be correlated with an insufficient synthesis of 5-hydroxytryptamine (5-HT) in the brain secondary to a decreased influx of Try.

A rare complication of carcinoÏd carcinoma

The normal metabolism of tryptophan, one of the essential amino acids, was discussed and the changes of this metabolism due to the metastasis of the carcinoid carcinoma and its psychiatric complications based on a central tryptophile deficiency were examined.

Carcinoid associated encephalitis successfully treated with tryptophan

Catatonia: the rise and fall of an intriguing psychopathological dimension

The significance of catatonic symptoms is not recognized in the current taxonomies despite the fact that this has major pharmacological treatment implications.

INITIAL MENTAL DISORDERS IN CARCINOMA OF PANCREAS AND STOMACH

There are several casuistic reports of early mental disorders in carcinoma of the pancreas (c.p.) usually in the form of depression, anxiety and insomnia, and there is usually a fairly high percentage of cases with initial mental disturbance without or coiicurrent with somatic symptoms such as pain and loss of weight.

Organic causes of mania.

Use of the somatostatin analogue octreotide acetate in the treatment of encephalopathy associated with carcinoid tumor. Case report.

A patient having metastatic carcinoid tumor who developed encephalopathy of uncertain etiology is described, and treatment with the somatostatin analogue octreotide acetate resulted in dramatic improvement in his mental status.

Delirium, clouding of consciousness and confusion.

Current interest in cognition should extend to delirium in which disorganization of cognitive processes is the chief feature, and dissatisfaction with the current classification of the so-called organic brain syndromes is justified.

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