MELTING, computing the melting temperature of nucleic acid duplex

@inproceedings{Nov2001MELTINGCT,
  title={MELTING, computing the melting temperature of nucleic acid duplex},
  author={Nicolas Le Nov},
  year={2001}
}
Summary: MELTING computes the enthalpy and entropy of an oligonucleotide duplex helix–coil transition, and then its melting temperature. The program uses the method of nearest-neighbours. The set of thermodynamic parameters can be easily customized. The program provides several correction methods for the concentration of salt. MELTING is a free program, available at no cost and open-source. Perl scripts are provided to show how MELTING can be used to construct more ambitious programs… CONTINUE READING

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