MEK Retinopathy. Clinical case reports.


CASE REPORTS Three clinical cases are presented of MEK retinopathy associated with the combination of cobimetinib and vemurafenib characterised by alteration of the retinal pigment epithelium and neurosensory detachment. Two of the cases conserved the vision of the unit, and the third developed a large bilateral neurosensory detachment with final visual acuity of 0.6 for the right eye and 0.1 for the left one. DISCUSSION The new therapeutic strategies against metastatic cutaneous melanoma condition the appearance of alterations of the pigmentary epithelium of the retina with serous detachments, leading to close monitoring with macular optical coherence tomography.

DOI: 10.1016/j.oftal.2017.03.005

Cite this paper

@article{Cabrera2017MEKRC, title={MEK Retinopathy. Clinical case reports.}, author={P Rocha Cabrera and E Quijada Fumero and M J Losada Castillo and J A Abreu Reyes and Jacob Lorenzo Morales}, journal={Archivos de la Sociedad Espanola de Oftalmologia}, year={2017} }