MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

  title={MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment},
  author={Sudhir Kumar and Koichiro Tamura and Masatoshi Nei},
  journal={Briefings in bioinformatics},
  volume={5 2},
With its theoretical basis firmly established in molecular evolutionary and population genetics, the comparative DNA and protein sequence analysis plays a central role in reconstructing the evolutionary histories of species and multigene families, estimating rates of molecular evolution, and inferring the nature and extent of selective forces shaping the evolution of genes and genomes. The scope of these investigations has now expanded greatly owing to the development of high-throughput… CONTINUE READING
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