MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: a randomised controlled trial protocol

@article{Santo2017MEDicationRA,
  title={MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: a randomised controlled trial protocol},
  author={Karla Santo and Clara K. Chow and Aravinda Thiagalingam and Kris Rogers and John Chalmers and Julie Redfern},
  journal={BMJ Open},
  year={2017},
  volume={7}
}
Introduction The growing number of smartphone health applications available in the app stores makes these apps a promising tool to help reduce the global problem of non-adherence to long-term medications. However, to date, there is limited evidence that available medication reminder apps are effective. This study aims to determine the impact of medication reminder apps on adherence to cardiovascular medication when compared with usual care for people with coronary heart disease (CHD) and to… 
Medication reminder applications to improve adherence in coronary heart disease: a randomised clinical trial
TLDR
Patients with CHD who used medication reminder apps had better medication adherence compared with usual care, and using apps with additional features did not improve this outcome further, suggesting medication apps are likely to help patients with chronic health conditions adhere to medicines.
Evaluating Reach, Acceptability, Utility, and Engagement with An App-Based Intervention to Improve Medication Adherence in Patients with Coronary Heart Disease in the MedApp-CHD Study: A Mixed-Methods Evaluation
TLDR
This mixed-methods evaluation suggests that, currently, young male patients with CHD are more likely to use such apps, that the apps were well-accepted and useful in reminding the patients to take the medications, and that the patients were engaged in regularly using the apps.
Reminders for medication adherence in Type 2 diabetes management apps
TLDR
Only 55.8% of diabetes management apps assessed for the presence of medication reminder features had a basic medication reminder function, although those that had them conformed to the characteristics of SMS reminders shown to be effective.
Digital Medication Adherence Support: Could Healthcare Providers Recommend Mobile Health Apps?
TLDR
A methodology for scientific and end-user (patient) mHealth evaluation to identify medication adherence apps search terms, to evaluate identified apps based on scientific criteria, and to report best smartphone apps evaluated by patients is developed.
Evaluating Reminders for Medication Adherence and Side Effects in M-Health Environment
TLDR
An analytical model is developed to evaluate different types of reminders for medication adherence and indicates that context-aware reminders perform better than simple reminders in improving medication adherence for willing patients in mobile health environment.
Do mobile device apps designed to support medication adherence demonstrate efficacy? A systematic review of randomised controlled trials, with meta-analysis
TLDR
Patients who use mobile apps to support them in taking medications are more likely to self-report adherence to medications than those in the comparator groups, and app usage may have a positive effect on patient adherence.
The impact of mobile application: "Friends of Heart" in knowledge and compliance of patients with coronary heart disease
TLDR
The use of the “Friends of Heart” application could improve compliance and knowledge of coronary heart disease patients.
Strengthening Medication Adherence Practices in Chronic Disease Patients-clinical Pharmacist Driven Focused Approach
TLDR
There is a growing concern for healthcare professionals to take initiative and strengthen the medication adherence practices and clinical pharmacist’s initiatives in this direction has been appreciated and documented.
Interventions that improve adherence to antihypertensive medications in coronary heart disease patients: a systematic review
TLDR
It is recommended that health service institutions should provide continuous education programmes, daily reminders and regular follow-ups for their patients who have CHD, and eight interventions were evaluated in total, three of which were considered effective.
Information Technology-based Interventions for Health Care Support in Patients with Chronic Kidney Disease: A Systematic Review
TLDR
Evidence indicates the potential of IT-based interventions (i.e. smartphone/PDA, computer, internet/web, telematic device) to support the health management of patients with CKD.
...
...

References

SHOWING 1-10 OF 48 REFERENCES
Effect of a reminder system using an automated short message service on medication adherence following acute coronary syndrome
TLDR
An automated SMS-based reminder system can potentially enhance medication adherence in ACS patients during the early post-discharge period, with better results among patients who received SMS reminders.
Smartphone medication adherence apps: potential benefits to patients and providers.
TLDR
Despite being untested, medication apps represent a possible strategy that pharmacists can recommend to nonadherent patients and incorporate into their practice.
Mobile Phone Apps to Improve Medication Adherence: A Systematic Stepwise Process to Identify High-Quality Apps
TLDR
Using the MARS instrument, high-quality apps were identified that were rated as being very interesting and entertaining, highly interactive and customizable, intuitive, and easy to use and to navigate as well as having a high level of visual appeal and good-quality information.
Effect of Lifestyle-Focused Text Messaging on Risk Factor Modification in Patients With Coronary Heart Disease: A Randomized Clinical Trial.
TLDR
Among patients with coronary heart disease, the use of a lifestyle-focused text messaging service compared with usual care resulted in a modest improvement in LDL-C level and greater improvement in other cardiovascular disease risk factors.
Interventions to improve medication adherence in coronary disease patients: A systematic review and meta-analysis of randomised controlled trials
TLDR
Simple one-component interventions might be a promising way to improve medication adherence in a CHD population, as they would be easier to replicate in different settings and on a large scale.
Mobile Telephone Text Messaging for Medication Adherence in Chronic Disease: A Meta-analysis.
TLDR
Mobile phone text messaging approximately doubles the odds of medication adherence in adults with chronic disease, and this increase translates into adherence rates improving from 50% to 67.8%, or an absolute increase of 17.8%.
Medication Adherence: Its Importance in Cardiovascular Outcomes
TLDR
The goals of the present report are to address different methods of measuring adherence, the prevalence of medicationNonadherence, the association between nonadherence and outcomes, the reasons for nonad adherence, and finally, interventions to improve medication adherence.
m-Health in Coronary Disease Preventive Care.
TLDR
The potential use of mHealth in a variety of medical conditions is discussed and some promising applications in CHD prevention are highlighted.
The implications of therapeutic complexity on adherence to cardiovascular medications.
TLDR
Medication use and prescription filling for patients with cardiovascular disease is complex, and strategies to reduce this complexity may help improve medication adherence.
...
...