Corpus ID: 26707795

MEDICINAL PROPERTIES OF MILK THISTLE WITH SPECIAL REFERENCE TO SILYMARIN AN OVERVIEW

@inproceedings{Das2008MEDICINALPO,
  title={MEDICINAL PROPERTIES OF MILK THISTLE WITH SPECIAL REFERENCE TO SILYMARIN AN OVERVIEW},
  author={S. K. Das and Shyamali Mukherjee},
  year={2008}
}
Milk Thistle, Silybum marianum Gaertn. plant has been used for centuries as a natural remedy for several diseases. Its active constituent, silymarin displays several medicinal properties, viz. antioxidant, hepatoprotective, cytoprotective, amelioration of hepatic collagen accumulation in advanced fibrosis, immunomodulatory activity, etc. Present paper summarizes various research reports on the medicinal properties of the plant with special reference to silymarin. 
A Review on Pharmacological, Cultivation and Biotechnology Aspects of Milk Thistle (Silybum marianum (L.) Gaertn.)
TLDR
This review summarized the accomplished investigations on aspects of medicinal, cultivation, biology and biotechnology of milk thistle. Expand
Phytotherapeutic properties of milk thistle seeds: An overview
TLDR
Milk thistle seed has anti-inflammatory, immunomodulatory, lipid and biliary effects, it also has antiviral, antitumor and other therapeutic properties, and is a very promising herbal drug. Expand
Silymarin and Its Role in Chronic Diseases.
TLDR
In this present chapter, a comprehensive attempt has been made to discuss the potential of silymarin in chronic disorders. Expand
Milk Thistle Seeds in Health
TLDR
Milk thistle seed has anti-inflammatory, immunomodulatory, lipid, and biliary effects, and has antiviral, antitumor, and other health beneficiary properties, and is a very promising natural drug. Expand
Milk Thistle ( Silybum marianum L. Gaert.) Seeds in Health
TLDR
Silymarin is used for the treatment of several liver diseases characterized by degenerative necrosis and functional impairment, including chronic liver disorders, and has antiviral, antitumor, and other health-beneficiary properties. Expand
Silybum marianum (Milk Thistle): Review on Its chemistry, morphology, ethno medical uses, phytochemistry and pharmacological activities
The oldest remedies identified to mankind are herbal medicines. India is recognized worldwide for its Ayurvedic treatment. India has rich history of using many plants for medicinal purposes. RemedialExpand
Plants as the basis for the development of environmentally friendly highly functional bioadditives for animals (review)
Presently, the use of plant components with antimicrobial, antiviral, antioxidant, anti-inflammatory, hepatoprotective and immunomodulatory effects is of particular interest for the preparation ofExpand
Overview of Silibinin anti-tumor effects
TLDR
A summary of the main molecular mechanisms involved in Silibinin anti-cancer effects, up to date utilities and important clinical trials have been presented and will help to optimize its pharmaceutical properties in cancer chemotherapeutic regimens. Expand
Effect of Silymarin as Natural Antioxidants and Antimicrobial Activity
ffect of silymarin as natural antioxidants and antimicrobial activity was main target of the present study. Physicochemical properties of the sunflower oil, and its fatty acid fractionated using GLCExpand
Medicinal plants: Future source of new drugs
TLDR
The aim of the present review is to understand the knowledge of the medicinal plants as a future source of herbal drugs in India. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 116 REFERENCES
Is silymarin hepatoprotective in alcoholic liver disease?
TLDR
The previous data on silymarin in ALD along with current evidence on the potential benefit of antioxidant therapies in ALd, justify a more systematic assessment of sily marin inALD. Expand
Milk Thistle (Silybum marianum) for the Therapy of Liver Disease
TLDR
Silymarin and its active constituent, silybin, have been reported to work as antioxidants scavenging free radicals and inhibiting lipid peroxidation, and to protect against genomic injury and stabilize mast cells, chelate iron, and slow calcium metabolism. Expand
A review of plants used in the treatment of liver disease: part 1.
  • S. Luper
  • Medicine
  • Alternative medicine review : a journal of clinical therapeutic
  • 1998
TLDR
When compared with Silybum, the hepatoprotective effect of Picrorhiza kurroa was found to be similar, or in many cases, superior to the effect of SILYbum. Expand
Herbal products for liver diseases: A therapeutic challenge for the new millennium
TLDR
Herbal extracts derived from licorice root, Phyllanthus amarus, milk thistle, Picrorhiza kurroa, and sho-saiko-to can serve as primary compounds for the development of specific hepatotropic drugs. Expand
Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine.
TLDR
Silymarin may prove to be a useful drug for hepatoprotection in hepatobiliary diseases and in hepatotoxicity due to drugs, as it is having a good safety profile, better patient tolerability and an effective drug at an affordable price. Expand
Protective effects of silymarin, a milk thistle (Silybium marianum) derivative on ethanol-induced oxidative stress in liver.
TLDR
It was observed that abstinence from ethanol might help in hepatic regeneration, and preventive measures were more effective than curative treatment. Expand
Selectivity of silymarin on the increase of the glutathione content in different tissues of the rat.
Silymarin, a flavonoid extracted from the seeds of the milk thistle, Silybum marianum, increases the redox state and the total glutathione content of the liver, intestine, and stomach of the rat. TheExpand
Silibinin, a plant extract with antioxidant and membrane stabilizing properties, protects exocrine pancreas from cyclosporin A toxicity
TLDR
Silibinin inhibits glucose-stimulated insulin release in vitro, while not affecting blood glucose concentration in vivo, which could be useful in the treatment of non-insulin-dependent diabetes mellitus and protects the exocrine pancreas from CiA toxicity. Expand
Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture
TLDR
It is demonstrated that milk thistle extract can promote neuronal differentiation and survival, suggesting potential benefits of chemicals in this plant on the nervous system. Expand
Future Directions for Research on Silybum marianum for Cancer Patients
  • S. Sagar
  • Medicine
  • Integrative cancer therapies
  • 2007
TLDR
Future research should focus on authentication of active chemicals, pharmacokinetics, adverse interactions and quality control, prevention of cancer initiation and progression, adjuvant therapy for specific cancers, and prevention of toxicity from anticancer therapies. Expand
...
1
2
3
4
5
...