MED12 mutations in uterine fibroids--their relationship to cytogenetic subgroups.

@article{Markowski2012MED12MI,
  title={MED12 mutations in uterine fibroids--their relationship to cytogenetic subgroups.},
  author={Dominique Nadine Markowski and Sabine Bartnitzke and Thomas Loening and Norbert Drieschner and Burkhard Maria Helmke and Joern Bullerdiek},
  journal={International journal of cancer},
  year={2012},
  volume={131 7},
  pages={
          1528-36
        }
}
Recurrent chromosomal alterations are found in roughly 20% of all uterine fibroids but in the majority cytogenetic changes are lacking. Recently, mutations of the gene mediator subcomplex 12 (MED12) have been detected in a majority of fibroids but no information is available whether or not they co-occur with cytogenetic subtypes as, e.g., rearrangements of the genes encoding high mobility group AT-hook (HMGA) proteins. In a total of 80 cytogenetically characterized fibroids from 50 patients, we… CONTINUE READING
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Essential roles of mesenchyme-derived betacatenin in mouse Müllerian duct morphogenesis

  • E Deutscher, H Hung-Chang Yao
  • Dev Biol
  • 2007
Highly Influential
4 Excerpts

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