MED, COMP, multilayered and NEIN: an overview of multiple epiphyseal dysplasia

@article{Lachman2004MEDCM,
  title={MED, COMP, multilayered and NEIN: an overview of multiple epiphyseal dysplasia},
  author={Ralph S. Lachman and Deborah Krakow and Daniel H Cohn and David L. Rimoin},
  journal={Pediatric Radiology},
  year={2004},
  volume={35},
  pages={116-123}
}
This overview covers the group of disorders that presents radiographically as multiple epiphyseal dysplasia (MED). The disorders include “classic MED” (Ribbing and Fairbank types): MED that is caused by mutations in the cartilage oligomeric matrix protein (COMP), type IX collagen, and matrilin 3 genes (MATN3); and MED with multilayered patella… CONTINUE READING