MECLOZINE AND FŒTAL ABNORMALITIES

@article{Diggory1962MECLOZINEAF,
  title={MECLOZINE AND F{\OE}TAL ABNORMALITIES},
  author={P. L. C. Diggory and John S. Tomkinson},
  journal={The Lancet},
  year={1962},
  volume={280},
  pages={1222-1223}
}
9 Citations
A Risk-Benefit Assessment of Pharmacological and Nonpharmacological Treatments for Nausea and Vomiting of Pregnancy
TLDR
A risk-benefit analysis of the literature on safety and effectiveness of pharmacotherapy and nontraditional therapy for nausea and vomiting of pregnancy (NVP) is summarised to provide evidence-based guidelines on the management of NVP.
The safety of drugs for the treatment of nausea and vomiting of pregnancy
TLDR
Different classes of antiemetics used to treat NVP are reviewed and it is discussed that some have better safety profiles than others, but most appear to be safe to use in pregnancy.
A case-control study of congenital abnormality and dimenhydrinate usage during pregnancy
TLDR
A lower rate of obstructive uropathy was found in infants born to mothers treated with dimenhydrinate during the first trimester of pregnancy than in infants whose mothers did not take the drug at that time.
Herbicides and congenital malformations: A review for the paediatrician
  • J. Pearn
  • Medicine
    Australian paediatric journal
  • 1985
TLDR
Following maternal exposure to herbicides and to dioxins, it has not been possible to produce teratogenic effects in primates, although fertility may be affected, and Epidemiological reports from Hungary, Italy, New Zealand, the United States, Europe and Australia have not revealed any positive evidence to indicate that a human herbicide teratogenesis syndrome exists.
Teratogenicity testing in humans: a method demonstrating safety of bendectin.
TLDR
No evidence is found to suggest that Bendectin is teratogenic in humans, but the incidence of birth defects in the offspring of women who took BendectIn during pregnancy is investigated.
Malformations caused by drugs in pregnancy.
  • W. Lenz
  • Medicine
    American journal of diseases of children
  • 1966
TLDR
A connection between quinine intake for artificial abortion and malformations has been assumed in selected cases, however, no unbiased study is available.
Evaluation of the teratogenic effect of meclizine in man.
DRUGS IN THE FIRST TRIMESTER OF PREGNANCY AND THE FETAL LIFE OF HOMO SAPIENS.
  • G. Mellin
  • Medicine
    American journal of obstetrics and gynecology
  • 1964