MECHANISMS OF ACQUIRED RESISTANCE IN MOUSE TYPHOID

@article{Blanden1966MECHANISMSOA,
  title={MECHANISMS OF ACQUIRED RESISTANCE IN MOUSE TYPHOID},
  author={R. Blanden and G. Mackaness and F. Collins},
  journal={The Journal of Experimental Medicine},
  year={1966},
  volume={124},
  pages={585 - 600}
}
Experiments in vitro comparing normal mouse peritoneal macrophages with cells from Salmonella typhimurium-infected mice have shown that the "immune" macrophages have conspicuously enhanced microbicidal properties. Whereas normal macrophages could inactivate only 50 to 60% of intracellular S. typhimurium pretreated with immune serum, cells from infected animals killed virtually all ingested organisms and did so at an accelerated rate. Macrophages from Listeria monocytogenes-infected mice were… Expand
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