MECHANISM OF DAMAGE TO THE CONTRALATERAL TESTIS IN RATS WITH AN ISCHAEMIC TESTIS

@article{Harrison1981MECHANISMOD,
  title={MECHANISM OF DAMAGE TO THE CONTRALATERAL TESTIS IN RATS WITH AN ISCHAEMIC TESTIS},
  author={Richard G. Harrison and David Iwan Lewis-Jones and M J Moreno de Marval and Robert Connolly},
  journal={The Lancet},
  year={1981},
  volume={318},
  pages={723-725}
}
A degenerating ischaemic rat testis produces damage to its contralateral testis. When ischaemic testes were grafted or injected as a homogenate for a week into littermate rats there was considerable damage to host testes. This damage was caused by an immunological response, demonstrated as an increase in cytotoxicity of host serum which increased immunofluorescence, particularly of the membrana propria, which had become thickened. Manipulation of the testis and its blood supply was sufficient… CONTINUE READING
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