MDS: roadblock to differentiation.

@article{Agarwal2012MDSRT,
  title={MDS: roadblock to differentiation.},
  author={Anupriya Agarwal},
  journal={Blood},
  year={2012},
  volume={120 10},
  pages={1968-9}
}
MDS is thought to be a disorder of hematopoietic stem cells (HSCs).2 Chromosomal abnormalities, mutations, and epigenetic changes have been reported in MDS progenitors.3,4 However, the earliest stage at which these molecular and pathogenic events occur and the functional consequences of these events has not been clearly established. In the present study, Will and colleagues functionally and molecularly characterize highly purified primitive stem cells and progenitors using technically… CONTINUE READING
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