MDR1 C3435T polymorphism and inflammatory bowel disease risk: a meta-analysis

  title={MDR1 C3435T polymorphism and inflammatory bowel disease risk: a meta-analysis},
  author={Jun Wang and Xufeng Guo and Shijie Yu and Jixiang Zhang and Jia Song and Mengyao Ji and Zhuo Cao and Jing Wang and Ya Liu and Weiguo Dong},
  journal={Molecular Biology Reports},
The C3435T polymorphism of the multidrug resistance gene (MDR1) has been implicated in inflammatory bowel disease (IBD) risk, but the reported results are inconsistent. Here we performed a meta-analysis to evaluate the association between C3435T polymorphism and the risk of IBD using all case–control studies published before February 2013 according to PubMed and Web of Science. A total of 13 case–control studies, including 6,757 cases and 4,295 controls, were included. Pooled odds ratio (OR… CONTINUE READING


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