MDMA in adolescent male rats: decreased serotonin in the amygdala and behavioral effects in the elevated plus-maze test.

@article{Faria2006MDMAIA,
  title={MDMA in adolescent male rats: decreased serotonin in the amygdala and behavioral effects in the elevated plus-maze test.},
  author={Raquel Santos Faria and Ana Magalh{\~a}es and Pedro Ribeiro Rocha Monteiro and Joana Gomes-da-Silva and Maria Am{\'e}lia Tavares and Teresa Summavielle},
  journal={Annals of the New York Academy of Sciences},
  year={2006},
  volume={1074},
  pages={643-9}
}
Long-term behavioral consequences of the neurotoxicity produced by 3,4-methylenedioxymethamphetamine (MDMA) in the adolescent rat are still mostly unknown. Here, adolescent male rats (postnatal day 45 PND [45]) were exposed to 10 mg/kg of MDMA, intraperitoneally, every 2 h for 6 h. Controls were given 0.9% saline in the same protocol. Ten days after exposure, the behavioral effects of MDMA were assessed in the elevated plus-maze (n = 6 per group). After behavioral testing, animals were… CONTINUE READING

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