MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone

@article{Dujardin2011MDM2AC,
  title={MDM2 and CDK4 immunohistochemistry is a valuable tool in the differential diagnosis of low-grade osteosarcomas and other primary fibro-osseous lesions of the bone},
  author={Fanny Dujardin and Matthieu Bui Nguyen Binh and Corinne Bouvier and Anne Gomez-Brouchet and Fr{\'e}d{\'e}rique Larousserie and Anne de Muret and Caroline Louis-Brennetot and Alain Aurias and J. M. Coindre and Louis C. Guillou and Florence Pedeutour and H{\'e}l{\`e}ne Duval and Christine Collin and G. Du Bouexic de Pinieux},
  journal={Modern Pathology},
  year={2011},
  volume={24},
  pages={624-637}
}
Low-grade osteosarcoma is a rare malignancy that may be subdivided into two main subgroups on the basis of location in relation to the bone cortex, that is, parosteal osteosarcoma and low-grade central osteosarcoma. Their histological appearance is quite similar and characterized by spindle cell stroma with low-to-moderate cellularity and well-differentiated anastomosing bone trabeculae. Low-grade osteosarcomas have a simple genetic profile with supernumerary ring chromosomes comprising… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 64 references

Similar Papers

Loading similar papers…