MDCK cells express serotonin-regulable 11beta-hydroxysteroid dehydrogenase type 2.

@article{Zallocchil2006MDCKCE,
  title={MDCK cells express serotonin-regulable 11beta-hydroxysteroid dehydrogenase type 2.},
  author={Marisa L Zallocchil and Mar{\'i}a Cristina Damasco and J. Carlos Calvo and Carlos Pedro Lantos and Laura Beatriz Matkovic},
  journal={Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al},
  year={2006},
  volume={30 3},
  pages={
          469-77
        }
}
Prior to this work, we found that adrenal as well as extra-adrenal factors activate the response of renal 11beta-hydroxysteroid dehydrogenase 2 to stressful situations. These results -showing ways through which the organism hinders the pathological occupation of mineralocorticoid receptors by glucocorticoids leading to sodium retention and hypertension- prompted the present study on the nature of the above-mentioned extra-adrenal factors. Serotonin was chosen because of its properties as a… CONTINUE READING

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