MCM2 expression levels predict diagnosis and prognosis in gastric cardiac cancer.

@article{Liu2013MCM2EL,
  title={MCM2 expression levels predict diagnosis and prognosis in gastric cardiac cancer.},
  author={Min Liu and Jinsong Li and Dong-ping Tian and Bo Huang and Seema Bairoliya Rosqvist and Min Su},
  journal={Histology and histopathology},
  year={2013},
  volume={28 4},
  pages={481-92}
}
BACKGROUND Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated markers Ki67 and PCNA. METHODS GCC and corresponding cardiac precancerous samples were immunostained with Ki67, MCM2 and PCNA antibodies. RESULTS 90% of dysplasia samples expressed… CONTINUE READING
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