MCM2 expression levels predict diagnosis and prognosis in gastric cardiac cancer.

@article{Liu2013MCM2EL,
  title={MCM2 expression levels predict diagnosis and prognosis in gastric cardiac cancer.},
  author={M. Liu and J. Li and D. Tian and Bo Huang and S. Rosqvist and M. Su},
  journal={Histology and histopathology},
  year={2013},
  volume={28 4},
  pages={
          481-92
        }
}
  • M. Liu, J. Li, +3 authors M. Su
  • Published 2013
  • Biology, Medicine
  • Histology and histopathology
  • BACKGROUND Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated markers Ki67 and PCNA. METHODS GCC and corresponding cardiac precancerous samples were immunostained with Ki67, MCM2 and PCNA antibodies. RESULTS 90% of dysplasia samples expressed… CONTINUE READING

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