xenograft model of human comedo ductal carcinoma in situ.

  title={ xenograft model of human comedo ductal carcinoma in situ.},
  author={F. Roy Miller and Steven J. Santner and Larry R Tait and Peter J. Dawson},
  journal={Journal of the National Cancer Institute},
  volume={92 14},
Ductal carcinoma in situ (DCIS) is becoming increasingly common, accounting for 25%–30% of newly diagnosed cases of breast cancer (1). The comedo type represents about 40% of the cases and carries the worst prognosis (2). The subsequent incidence of recurrence in patients presenting previously with comedo DCIS was 20% compared with 5% for noncomedo DCIS in one study (3). National Surgical Adjuvant Breast and Bowel Project Protocol B-17 reported a 40% incidence of ipsilateral breast cancer after… CONTINUE READING
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