MARCKS: a case of molecular exaptation?

  title={MARCKS: a case of molecular exaptation?},
  author={Jeremy J. Ramsden},
  journal={The international journal of biochemistry & cell biology},
  volume={32 5},
  • Jeremy J. Ramsden
  • Published 2000 in
    The international journal of biochemistry & cell…
MARCKS (myristoylated alanine-rich C kinase substrate, 32 kDa) and its 20 kDa brother MARCKS-related protein (MRP) are abundant, widely distributed proteins unusually rich in alanine and glutamic acid, and with lysines, serines and phenylalanines concentrated in a compact "effector domain" (ED) near the middle of the sequence. Its conformation in solution appears to be labile, with little evidence for definite secondary structure. MARCKS (and MRP) interact inter alia with lipid bilayer… CONTINUE READING
Highly Cited
This paper has 28 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.


Publications citing this paper.
Showing 1-10 of 17 extracted citations

MARCKS and MARCKS-like proteins in development and regeneration

Journal of Biomedical Science • 2018
View 5 Excerpts
Highly Influenced

Isolation and characterization of a Xenopus gene (XMLP) encoding a MARCKS-like protein.

The International journal of developmental biology • 2001
View 2 Excerpts
Highly Influenced