MAP kinase pathway is involved in IGF-1-stimulated proliferation of human retinal pigment epithelial cells (hRPE).

Abstract

PURPOSE To investigate the mitogenic activity of insulin-like growth factor-1 (IGF-1) on the proliferation of human retinal pigment epithelial cells (hRPE) and to elucidate the role of vascular endothelial growth factor (VEGF) and MAP kinase (MAPK) in the IGF-1 signaling cascade. METHODS Human RPE specimens were obtained from postmortem non-pathological… (More)
DOI: 10.3109/02713680903177890

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@article{Weng2009MAPKP, title={MAP kinase pathway is involved in IGF-1-stimulated proliferation of human retinal pigment epithelial cells (hRPE).}, author={Christina Y Weng and Piyush C Kothary and Angela J Verkade and David M. Reed and Monte A del Monte}, journal={Current eye research}, year={2009}, volume={34 10}, pages={867-76} }