MAP kinase is activated during mesoderm induction in Xenopus laevis.

@article{Hartley1994MAPKI,
  title={MAP kinase is activated during mesoderm induction in Xenopus laevis.},
  author={Rebecca S. Hartley and Andrea L. Lewellyn and James L. Maller},
  journal={Developmental biology},
  year={1994},
  volume={163 2},
  pages={521-4}
}
MAP kinase (MAPK) is activated in animal cap explants from Xenopus embryos in response to mesoderm induction by FGF. This activation is rapid, appearing within 1 min of treatment with FGF, and prolonged, lasting for at least 2 hr. By immunoblot analysis, this activation of MAPK is coupled with an electrophoretic shift to the slowly migrating, phosphorylated form of MAPK. Activin-stimulated mesoderm induction also results in the activation of MAPK, but only upon prolonged exposure. However… CONTINUE READING