MAP Kinases and Prostate Cancer

@inproceedings{RodrguezBerriguete2012MAPKA,
  title={MAP Kinases and Prostate Cancer},
  author={Gonzalo Rodr{\'i}guez-Berriguete and Benito Fraile and Pilar Mart{\'i}nez-Onsurbe and Gabriel Olmedilla and Ricardo Paniagua and Mar Royuela},
  booktitle={Journal of signal transduction},
  year={2012}
}
  • Gonzalo Rodríguez-Berriguete, Benito Fraile, +3 authors Mar Royuela
  • Published in
    Journal of signal…
    2012
  • Biology, Medicine
  • The three major mitogen-activated protein kinases (MAPKs) p38, JNK, and ERK are signal transducers involved in a broad range of cell functions including survival, apoptosis, and cell differentiation. Whereas JNK and p38 have been generally linked to cell death and tumor suppression, ERK plays a prominent role in cell survival and tumor promotion, in response to a broad range of stimuli such as cytokines, growth factors, ultraviolet radiation, hypoxia, or pharmacological compounds. However… CONTINUE READING

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