MAP(2.0)3D: a sequence/structure based server for protein engineering.

  title={MAP(2.0)3D: a sequence/structure based server for protein engineering.},
  author={R. Verma and U. Schwaneberg and D. Roccatano},
  journal={ACS synthetic biology},
  volume={1 4},
  • R. Verma, U. Schwaneberg, D. Roccatano
  • Published 2012
  • Biology, Medicine
  • ACS synthetic biology
  • The Mutagenesis Assistant Program (MAP) is a web-based tool to provide statistical analyses of the mutational biases of directed evolution experiments on amino acid substitution patterns. MAP analysis assists protein engineers in the benchmarking of random mutagenesis methods that generate single nucleotide mutations in a codon. Herein, we describe a completely renewed and improved version of the MAP server, the MAP(2.0)3D server, which correlates the generated amino acid substitution patterns… CONTINUE READING
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