MAOA genotype, social exclusion and aggression: an experimental test of a gene-environment interaction.

@article{GallardoPujol2013MAOAGS,
  title={MAOA genotype, social exclusion and aggression: an experimental test of a gene-environment interaction.},
  author={David Gallardo-Pujol and Antonio Andr{\'e}s-Pueyo and Alberto Maydeu-Olivares},
  journal={Genes, brain, and behavior},
  year={2013},
  volume={12 1},
  pages={140-5}
}
In 2002, Caspi and colleagues provided the first epidemiological evidence that genotype may moderate individuals' responses to environmental determinants. However, in a correlational study great care must be taken to ensure the proper estimation of the causal relationship. Here, a randomized experiment was performed to test the hypothesis that the MAOA gene promoter polymorphism (MAOA-LPR) interacts with environmental adversity in determining aggressive behavior using laboratory analogs of real… CONTINUE READING
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