MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males

@article{Du2004MAOAGP,
  title={MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males},
  author={Lisheng Du and David Bakish and Arun V Ravindran and Pavel D. Hrdina},
  journal={NeuroReport},
  year={2004},
  volume={15},
  pages={2097-2101}
}
We investigated whether the genetic variants of the MAO-A gene were associated with major depression and/or the clusters of depressive symptoms. The EcoRV and the uVNTR polymorphisms were studied in a population of 191 patients with major depression and 233 control subjects. The EcoRV polymorphism was found to be associated with depression in males but not in females. Haplotype analysis revealed that one of the haplotypes (EcoRV2-uVNTR1) was significantly more frequent among male patients than… 

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