MANTIS: a phylogenetic framework for multi-species genome comparisons

@article{Tzika2007MANTISAP,
  title={MANTIS: a phylogenetic framework for multi-species genome comparisons},
  author={Athanasia C. Tzika and Rapha{\"e}l Helaers and Yves Van de Peer and Michel C. Milinkovitch},
  journal={Bioinformatics},
  year={2007},
  volume={24 2},
  pages={
          151-7
        }
}
MOTIVATION Practitioners of comparative genomics face huge analytical challenges as whole genome sequences and functional/expression data accumulate. Furthermore, the field would greatly benefit from a better integration of this wealth of data with evolutionary concepts. RESULTS Here, we present MANTIS, a relational database for the analysis of (i) gains and losses of genes on specific branches of the metazoan phylogeny, (ii) reconstructed genome content of ancestral species and (iii) over… CONTINUE READING

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