MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives.

@article{Seeley2011MALDIIM,
  title={MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives.},
  author={Erin H. Seeley and Richard M Caprioli},
  journal={Trends in biotechnology},
  year={2011},
  volume={29 3},
  pages={136-43}
}
The molecular complexity of biological tissue and the spatial and temporal variation in the biological processes involved in human disease requires new technologies and new approaches to provide insight into disease processes. Imaging mass spectrometry is an effective tool that provides molecular images of tissues in the molecular discovery process. The analysis of human tissue presents special challenges and limitations because the heterogeneity among human tissues and diseases is much greater… CONTINUE READING

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