MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications

@article{Balluff2011MALDIIM,
  title={MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications},
  author={Benjamin Balluff and C{\'e}drik D Sch{\"o}ne and Heinz Hoefler and Axel Walch},
  journal={Histochemistry and Cell Biology},
  year={2011},
  volume={136},
  pages={227-244}
}
Matrix assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) is a method that allows the investigation of the molecular content of tissues within its morphological context. Since it is able to measure the distribution of hundreds of analytes at once, while being label free, this method has great potential which has been increasingly recognized in the field of tissue-based research. In the last few years, MALDI-IMS has been successfully used for the molecular assessment of… CONTINUE READING