MAEL contributes to gastric cancer progression by promoting ILKAP degradation

@inproceedings{Zhang2017MAELCT,
  title={MAEL contributes to gastric cancer progression by promoting ILKAP degradation},
  author={X Zhang and Yichong Ning and Yuzhong Xiao and Huaxin Duan and Guifang Qu and Xin Liu and Yan Du and Dejian Jiang and Jianlin Zhou},
  booktitle={Oncotarget},
  year={2017}
}
  • X Zhang, Yichong Ning, +6 authors Jianlin Zhou
  • Published in Oncotarget 2017
  • Medicine
  • The cancer-testis gene MAEL is involved in the development and progression of bladder, liver and colorectal cancers. However, its role in other cancers is unclear. By systematically analyzing transcriptomics and genomics data from various cancer databases, we identified that the MAEL gene is aberrantly elevated in gastric cancer (GC) tissues and that its expression is strongly negatively correlated with DNA methylation (Pearson's correlation coefficient = -0.675). Survival analysis revealed… CONTINUE READING

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