M cell transport of Vibrio cholerae from the intestinal lumen into Peyer's patches: a mechanism for antigen sampling and for microbial transepithelial migration.

@article{Owen1986MCT,
  title={M cell transport of Vibrio cholerae from the intestinal lumen into Peyer's patches: a mechanism for antigen sampling and for microbial transepithelial migration.},
  author={Robert L. Owen and Nathaniel F. Pierce and R T Apple and William C Cray},
  journal={The Journal of infectious diseases},
  year={1986},
  volume={153 6},
  pages={1108-18}
}
Viable Vibrio cholerae O1 were inoculated into the intestinal lumen of nonimmune rabbits. The vibrios were phagocytosed by M cells over Peyer's patch lymphoid follicles, carried in vesicles through the epithelium, and discharged among underlying lymphocytes and macrophages. Autoradiography of V. cholerae labeled with [2-3H]adenine confirmed transport. Indigenous bacteria with and without capsules were also taken up from control loops and carried through M cells into Peyer's patches. V. cholerae… CONTINUE READING

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