M-band: a safeguard for sarcomere stability?

@article{Agarkova2003MbandAS,
  title={M-band: a safeguard for sarcomere stability?},
  author={Irina Agarkova and Elisabeth Ehler and Stephan Lange and Roman Schoenauer and J. -C. Perriard},
  journal={Journal of Muscle Research & Cell Motility},
  year={2003},
  volume={24},
  pages={191-203}
}
The sarcomere of striated muscle is a very efficient machine transforming chemical energy into movement. However, a wrong distribution of the generated forces may lead to self-destruction of the engine itself. A well-known example for this is eccentric contraction (elongation of the sarcomere in the activated state), which damages sarcomeric structure and leads to a reduced muscle performance. The goal of this review is to discuss the involvement of different cytoskeletal systems, in particular… CONTINUE READING
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