Lyt-2- T cell-independent functions of Lyt-2+ cells stimulated with antigen or concanavalin A.

@article{Boehmer1984Lyt2TC,
  title={Lyt-2- T cell-independent functions of Lyt-2+ cells stimulated with antigen or concanavalin A.},
  author={Harald von Boehmer and Pawel Kisielow and W L Leiserson and Werner Haas},
  journal={Journal of immunology},
  year={1984},
  volume={133 1},
  pages={59-64}
}
Approximately 30% of cytolytic Lyt-2+ clones from primed mice are able to proliferate autonomously, i.e., independent of IL 2 derived from Lyt-2- cells after antigenic stimulation. H-2K- or -D-restricted induction of Lyt-2+ cells to autonomous proliferation requires Ia+ stimulator cells. A strict correlation was observed between the ability of Lyt-2+ clones to proliferative autonomously and to induce DH. Eventually, the growth of all Lyt-2+ cytolytic clones becomes dependent on exogenous IL 2… CONTINUE READING

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