Lysosomes in Skeletal Muscle Tissue

@article{Canonico1970LysosomesIS,
  title={Lysosomes in Skeletal Muscle Tissue},
  author={Peter G. Canonico and John W. C. Bird},
  journal={The Journal of Cell Biology},
  year={1970},
  volume={45},
  pages={321 - 333}
}
Postnuclear supernates from homogenates of skeletal muscle from rats subjected to starvation, injections of Triton WR-1339, dextran-500, and dextran + corticosterone were fractionated by means of rate and isopycnic zonal centrifugation in sucrose-0.02 M KCl gradients. Zonal fractions were analyzed for protein, RNA, cytochrome oxidase, and up to six acid hydrolases. The results indicate the presence of two groups of lysosome-like particles. One group contributes approximately 95% of the… CONTINUE READING
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