Lysosomal tracking with a cationic naphthalimide using multiphoton fluorescence lifetime imaging microscopy.

@article{Li2017LysosomalTW,
  title={Lysosomal tracking with a cationic naphthalimide using multiphoton fluorescence lifetime imaging microscopy.},
  author={Meng Li and Haobo Ge and Vincenzo Mirabello and Rory L. Arrowsmith and Gabriele I. Kociok-K{\"o}hn and Stanley W Botchway and Weihong Zhu and Sofia I Pascu and Tony D James},
  journal={Chemical communications},
  year={2017},
  volume={53 81},
  pages={11161-11164}
}
A naphthalimide-based chemosensing motif turns ON the fluorescence emission in solution in the presence of aqueous iron(iii) chloride, and maintains this property in living cancer cells. The emission response to Fe(iii) ions occurs simultaneously with a change in pH. The protonation of methyl piperazine-conjugated naphthalimide promotes its lysosomal… CONTINUE READING