Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats.

@article{Capel2009LysosomalAP,
  title={Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats.},
  author={Frederic Capel and Magalie Prod'homme and Daniel M B{\'e}chet and Daniel Taillandier and Mich{\`e}le Balage and Didier Attaix and Lydie Combaret},
  journal={The Journal of nutritional biochemistry},
  year={2009},
  volume={20 8},
  pages={570-6}
}
Skeletal muscle proteolysis is inhibited by oral feeding in the young and mature but not in the elderly. However, the proteolytic pathway(s) responsible for the decreased muscle proteolysis in the postprandial (PP) state is (are) unknown in the young. Moreover, muscle proteolysis is inhibited by both insulin (INS) and amino acids (AA) in vitro, but their respective roles on specific proteolytic pathways in vivo remain to be elucidated. The aim of this study was to investigate the respective… CONTINUE READING
Highly Cited
This paper has 107 citations. REVIEW CITATIONS

4 Figures & Tables

Topics

Statistics

050100150201020112012201320142015201620172018
Citations per Year

108 Citations

Semantic Scholar estimates that this publication has 108 citations based on the available data.

See our FAQ for additional information.