Lysosomal acid phosphatase is transported to lysosomes via the cell surface.

@article{Braun1989LysosomalAP,
  title={Lysosomal acid phosphatase is transported to lysosomes via the cell surface.},
  author={Manfred Braun and Abdul Waheed and Kurt von Figura},
  journal={The EMBO journal},
  year={1989},
  volume={8 12},
  pages={3633-40}
}
Lysosomal acid phosphatase (LAP) is transported as a transmembrane protein to dense lysosomes. The pathway of LAP to lysosomes includes the passage through the plasma membrane. LAP is transported from the trans-Golgi to the cell surface with a half-time of less than 10 min. Cell surface LAP is rapidly internalized. Most of the internalized LAP is transported back to the cell surface. On average, each LAP molecule cycles greater than 15 times between the cell surface and the endosomes before it… CONTINUE READING

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